This study used Ex-post Facto research design to investigate the contributions of Zamfara state Skills Acquisition programme on reduction of poverty among youths in Zamfara West Senatorial District. Human capital theory was used as a theoretical framework, the population for the study was 1900 and sample size was 320 based on Kreycie and Morgan (1971) table of determining sample size. Youths Skills Acquisition Programme on Reduction of Poverty Questionnaire (YSAPPRQ) for graduates, Youths Skills Acquisition Programme on Reduction of Poverty Questionnaire (YSAPPRQ) for instructors and official documents were used for data collection. The data were analyzed using frequency and percentages. The study found out that there were different skills acquisition programme provided by the Zamfara State that are empowering economically in nature and that has the capacity for reduction of poverty. The programme also has the indicators of contributions on reduction of poverty such as financial strength, wealth creation, job creation, occupational skills and economic self-reliance. The study also found out that insufficient funding, inadequate government and community support, inadequate learning equipment, inadequate instructional materials; lack of qualified, skilled instructors and also absence of staff training development have negatively affected the skill acquisition programme. The study recommended among others that since the programme has potential for reduction of poverty it should be sustained by incorporating the beneficiary communities in its management and financial supports.